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Ion-Exchange SCX SPE Cartridge, 100-200mg

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Catalog NumberACMA00046261
DescriptionStrong cation exchange(SCX) SPE cartridge is a silica-based benzenesulfonic acid-based filler. Its negatively charged sulfonic acid group has a strong cation exchange capacity, and the benzene ring has certain hydrophobic retention. SCX extracts positively charged basic compounds such as amines.
ApplicationDetection of drug abuse, such as amphetamine;
Analysis of drugs and their metabolites in biological matrices;
Detection of pesticides and antibiotic residues in foods, such as macrolides.
Used for the purification and concentration of proteins and peptides with cationic charges, aiding in proteomic studies and mass spectrometry analysis.
Isolate and purify cationic drug compounds and metabolites from biological samples for pharmaceutical analysis.
Extract and preconcentrate cationic contaminants, such as heavy metal ions, from water and soil samples.
Separate and analyze cationic compounds like amino acids and certain additives in food and beverages.
FeatureLower pKa.
Strong cation exchange and reversed double retention;
By adjusting the pH value, the charged state of the sulfonic acid group can be changed to facilitate elution.
Functional Groupsilica-based benzenesulfonic acid
Maximum Sample Load5mg-10mg
Minimum Elution Volume200-500μL
Particle Size40-75μm
Pore Size70 Å
Size100-200mg
Specific Surface Area510 m 2/g
Volume3mL

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