Anion Exchange Column



The anion exchange columns are similar to the cation exchange columns, the difference is that the type of resins in the stationary phase is different. The resins in the anion exchange column can be divided into strong base type and weak base type. Because it is based on polyphenylene matrix material, the anion exchange columns are most suitable for the analysis of small molecular weight sugars, amino acids, nucleic acid bases, and small candidate drugs. The resins are loaded into the exchange column in accordance with strict operating specifications. After the customer receives our exchange column, please remember to drop or bump it, otherwise it will affect the performance. Before using the new column or performing formal analysis, please wash the exchange column with at least 20 column volumes of mobile phase in advance to make the exchange column reach equilibrium. Pay attention to cleaning and storage after use, and it should be stored in a certain concentration of solvent, no matter whether it is short-term or long-term.


One of the applications of anion exchange columns is to adsorb metal ions. Taking hexavalent chromium as an example, as a well-known carcinogen, it can be released into the environment from industries such as leather tanning, electroplating, and dyes. Since the commonly used oxidation-reduction method and precipitation method will produce solid waste, there are certain limitations. On the other hand, typical layered double hydroxide (LDH) inorganic anion exchangers, although low in price, have relatively slow adsorption kinetics for chromium. The metal organic framework (MOF) has organic groups with strong binding affinity to toxic ions and can be used as an ideal adsorbent. This functionalized material that combines the organic functional groups of the amorphous organic resin with the ordered porous structure crystalline MOF can be called metal organic resins (MORs), such as [Zr6O4(OH)4(NH3+ -BDC)6)]Cl6MOR (MOR-1). The anion exchange composite material formed by the combination of MOP and alginic acid (HA) can adsorb hexavalent chromium in the presence of a large excess of competing ions (Cl-, Br-, NO3-, SO42-, etc.), In addition, the anion column can be easily regenerated and reused many times with almost no loss of capacity.(Sofia Rapti, et al., 2016)

Anion Exchange Column

Typical Applications

  • Oligonucleotide analysis
  • Remove organic matter in water
  • Carbohydrate separation

As an expert in the field of ionic resins, Alfa Chemistry offers a variety of models of anion exchange columns. We can also provide customized ion resins and exchange columns according to your special needs. Our goal is to use a comprehensive product line to help you solve any problems related to ionic resins. If you are interested in our anion exchange columns, please contact us.


  1. Sofia Rapti, et al. Selective capture of hexavalent chromium from an anion-exchange column of metal organic resin-alginic acid composite[J]. Chemical Science, 2016.

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